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Smart Investors Daily
AP

NASDAQ · APVO

Aptevo Therapeutics Inc.

Healthcare · Biotechnology

$1.36

Up+$0.01 (+0.74%)

Updated Nov 4, 2026, 4:09 AM

SID Score

3.6/10

Composite research score

Smart Money

—

Institutional and insider signal

Market cap
12.03M
P/E ratio
-0.06
Dividend yield
0.00%
52-week range
$1.25 – $6.74
Volume
13.98K
Avg. volume
182.09K

Price performance · APVO

APVO price history

1M range · 21 trading sessions · Daily adjusted prices

Prices through Nov 3, 2026

APVO closed at $1.36 after 21 trading sessions, down 24.23% for the selected period.

Last close
$1.36
Period change
-24.23%
Period low
$1.28
Period high
$1.84
Daily close
View OHLC price history
APVO OHLC price history, latest 40 sessions
DateOpenHighLowCloseVolume
Nov 3, 2026$1.44$1.44$1.31$1.3613.98K
Nov 2, 2026$1.3925$1.3976$1.3294$1.3523.05K
Oct 30, 2026$1.36$1.3864$1.31$1.3428.69K
Oct 29, 2026$1.32$1.41$1.31$1.3658.51K
Oct 28, 2026$1.36$1.3699$1.26$1.3042.35K
Oct 27, 2026$1.55$1.58$1.2525$1.2880.7K
Oct 26, 2026$1.74$1.74$1.43$1.50123.73K
Oct 23, 2026$1.61$1.6362$1.60$1.617.18K
Oct 22, 2026$1.605$1.64$1.60$1.615.29K
Oct 21, 2026$1.63$1.65$1.60$1.608.69K
Oct 20, 2026$1.6004$1.65$1.60$1.61512.57K
Oct 19, 2026$1.655$1.655$1.5682$1.608.43K
Oct 16, 2026$1.73$1.73$1.60$1.6231.62K
Oct 15, 2026$1.73$1.74$1.70$1.7011.31K
Oct 14, 2026$1.73$1.78$1.71$1.7322.25K
Oct 13, 2026$1.79$1.79$1.70$1.7385.93K
Oct 12, 2026$1.79$1.97$1.76$1.8363286.36K
Oct 9, 2026$1.79$1.81$1.78$1.796.82K
Oct 8, 2026$1.77$1.84$1.77$1.8026.9K
Oct 7, 2026$1.76$1.85$1.76$1.8412.15K
Oct 6, 2026$1.82$1.92$1.79$1.79535.4K

Latest APVO news

The latest Smart Investors Daily articles mentioning APVO.

APVO research

Overview

Company profile and research snapshot.

Company profile

Aptevo Therapeutics Inc is a clinical-stage research and development biotechnology company focused on developing novel immunotherapeutic candidates for the treatment of different forms of cancer. Its clinical candidates are; ALG.APV-527, which targets co-stimulatory receptors and tumor antigens, and CD3xCD123, which is being developed as a potential treatment of frontline acute myelogenous leukemia. The company's preclinical candidates, APVO711, APVO0442, and APVO603, are being developed using the ADAPTIR modular protein technology platform. The company's versatile and robust ADAPTIR and ADAPTIR-FLEX platforms are designed to generate monospecific, bispecific, and multi-specific antibody candidates that are capable of enhancing the human immune system against cancer cells.

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Analyst outlook

Consensus and target data currently published for this company.

Consensus
Buy
Average target
$428.40
Implied upside
—
Analysts
7
APVO recent ratings
DateFirmRatingTarget
Sep 23, 2024Roth MKMBuy—
May 13, 2022Piper SandlerOverweight—
May 28, 2021Roth CapitalBuy—
Nov 11, 2020Piper SandlerOverweight—
Apr 11, 2018Roth CapitalBuy—
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News briefing

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Benzinga · Aug 14, 2026

Aptevo Therapeutics Q2 EPS $(5.31) Beats $(6.16) Estimate

Aptevo Therapeutics (NASDAQ:APVO) reported quarterly losses of $(5.31) per share which beat the analyst consensus estimate of $(6.16) by 13.8 percent. This is a 96.49 percent increase over losses of $(151.20) per share

accessnewswire.com · Dec 9, 2025

Aptevo Therapeutics Highlights Compelling Safety and Strong Remission Rates for Mipletamig in Frontline AML at ASH 2025

100% of patients in Cohorts 1-3 remain free of cytokine release syndrome CRIS-7-derived CD3 design underpins a controlled T-cell response, supporting the differentiated safety profile, combinability with standard of care SEATTLE, WA / ACCESS Newswire / December 9, 2025 / Aptevo Therapeutics Inc. (NASDAQ:APVO), a clinical-stage biotechnology company focused on developing novel immune-oncology therapeutics based on its proprietary ADAPTIR™ and ADAPTIR-FLEX™ platform technologies, presented preliminary results from its ongoing Phase 1b/2 RAINIER study evaluating mipletamig, a CD123 x CD3 bispecific molecule, in combination with azacitidine and venetoclax (AZA/VEN) for newly diagnosed acute myeloid leukemia (AML) patients who are unfit for intensive chemotherapy. The data were presented on December 8, 2025, in a poster session at the American Society of Hematology (ASH) Annual Meeting.

AI research layers

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