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Smart Investors Daily
UP

NASDAQ · UPB

Upstream Bio, Inc.

Healthcare · Biotechnology

$5.31

Up+$0.00 (+0.00%)

Updated Sep 18, 2026, 2:27 PM

SID Score

2.9/10

Composite research score

Smart Money

Institutional and insider signal

Market cap
1.48B
P/E ratio
-14.14
Dividend yield
0.00%
52-week range
$5.27 – $10.67
Volume
533.87K
Avg. volume
437.05K

Price performance

UPB price history

1M range · 20 trading sessions · Daily adjusted prices

UPB closed at $5.31 after 20 trading sessions, down 22.48% for the selected period.

Last close
$5.31
Period change
-22.48%
Period low
$5.31
Period high
$7.18
Daily close
View OHLC price history
UPB OHLC price history, latest 40 sessions
DateOpenHighLowCloseVolume
Sep 17, 2026$5.44$5.48$5.235$5.31533.87K
Sep 16, 2026$5.49$5.54$5.27$5.33497.24K
Sep 15, 2026$5.81$5.81$5.455$5.48421.27K
Sep 14, 2026$5.75$5.87$5.70$5.81491.02K
Sep 11, 2026$5.84$5.84$5.65$5.73501.31K
Sep 10, 2026$5.86$5.86$5.67$5.75562.41K
Sep 9, 2026$6.14$6.20$5.77$5.96726.24K
Sep 8, 2026$6.01$6.21$5.77$6.19952.24K
Sep 4, 2026$6.00$6.23$5.965$6.01643.27K
Sep 3, 2026$6.49$6.49$5.77$6.081.35M
Sep 2, 2026$6.62$6.98$6.41$6.48515.76K
Sep 1, 2026$6.58$6.72$6.50$6.55476.49K
Aug 31, 2026$6.64$6.77$6.44$6.62895.01K
Aug 28, 2026$6.71$6.79$6.60$6.69445.48K
Aug 27, 2026$7.11$7.14$6.78$6.79335.06K
Aug 26, 2026$7.18$7.31$6.90$7.13432.93K
Aug 25, 2026$6.68$7.18$6.55$7.18554.42K
Aug 24, 2026$7.00$7.11$6.46$6.61538.55K
Aug 21, 2026$6.91$7.0062$6.85$6.97434.24K
Aug 20, 2026$7.48$7.555$6.745$6.85592.94K

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