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Smart Investors Daily
SP

NASDAQ · SPRB

Spruce Biosciences, Inc.

Healthcare · Biotechnology

$55.17

Down-$1.69 (-2.96%)

Updated Sep 16, 2026, 10:24 AM

SID Score

4.5/10

Composite research score

Smart Money

Institutional and insider signal

Market cap
51.65M
P/E ratio
-1.12
Dividend yield
0.00%
52-week range
$7.26 – $240.00
Volume
110.11K
Avg. volume
571.26K

Price performance

SPRB price history

1M range · 20 trading sessions · Daily adjusted prices

SPRB closed at $55.17 after 20 trading sessions, up 4.39% for the selected period.

Last close
$55.17
Period change
+4.39%
Period low
$51.58
Period high
$63.40
Daily close
View OHLC price history
SPRB OHLC price history, latest 40 sessions
DateOpenHighLowCloseVolume
Sep 15, 2026$55.99$56.36$54.51$55.165110.11K
Sep 14, 2026$53.28$57.55$52.66$56.85102.62K
Sep 11, 2026$54.78$56.08$53.09$53.7088.51K
Sep 10, 2026$55.61$57.50$54.03$54.35118.76K
Sep 9, 2026$58.52$59.01$55.7001$55.7496.36K
Sep 8, 2026$57.39$60.51$56.60$59.09193.05K
Sep 4, 2026$57.37$58.19$56.57$57.93104.95K
Sep 3, 2026$59.76$60.315$57.30$57.71116.62K
Sep 2, 2026$56.52$60.13$56.52$59.67268.14K
Sep 1, 2026$58.01$58.05$55.34$55.6058.13K
Aug 31, 2026$60.54$60.90$57.575$58.9744.94K
Aug 28, 2026$62.115$62.98$59.895$60.7839.96K
Aug 27, 2026$62.00$63.56$60.55$63.3080.3K
Aug 26, 2026$64.50$64.50$60.46$61.4891.77K
Aug 25, 2026$58.82$64.15$58.00$63.40147.3K
Aug 24, 2026$53.04$58.92$51.16$58.65138.81K
Aug 21, 2026$52.48$53.00$49.03$51.5862.31K
Aug 20, 2026$52.83$52.89$50.50$51.98521.64K
Aug 19, 2026$54.18$54.93$52.02$52.9688.35K
Aug 18, 2026$51.305$53.95$50.80$52.84571.41K

Latest SPRB news

The latest Smart Investors Daily articles mentioning SPRB.

SPRB research

Overview

Company profile and research snapshot.

Company profile

Spruce Biosciences Inc is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with unmet medical needs. The pipeline products of the company include Tralesinidase Alfa (TA-ERT), and Tildacerfont/ Cortibon, a Companion Diagnostic, developed in partnership with HMNC Brain Health.

Visit company website

Analyst outlook

Consensus and target data currently published for this company.

Consensus
Average target
$209.50
Implied upside
Analysts
SPRB recent ratings
DateFirmRatingTarget
Aug 17, 2026GuggenheimBuy
Aug 13, 2026CitizensMarket Outperform
Jul 13, 2026B. Riley SecuritiesBuy
Jun 16, 2026GuggenheimBuy
Jun 9, 2026Jones TradingBuy
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