Yahoo · Oct 28, 2026
Palisade Bio Announces First Patient Dosed in Global Phase 2b ASCENTRA-UC Study Evaluating Once-Daily Oral PALI-2108 for the Treatment of Ulcerative Colitis
PALI-2108 is an investigational, gut-activated, once-daily oral PDE4 inhibitor prodrug designed for sustained exposure and anti-inflammatory activity with the potential to improve tolerability 29 of 30 planned U.S. sites already activated Global expansion progressing toward ~115 total sites, with CTA clearance in Canada and submissions under review in Europe and other international countries 12-week induction topline results expected Q4 2027 Denver, CO, Oct. 28, 2026 (GLOBE NEWSWIRE) -- Palisade

