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Smart Investors Daily
IO

NASDAQ · IONS

Ionis Pharmaceuticals, Inc.

Healthcare · Biotechnology

$43.52

Down-$0.87 (-1.96%)

Updated Nov 2, 2026, 3:51 AM

SID Score

4.3/10

Composite research score

Smart Money

58/100

Neutral

Market cap
12.57B
P/E ratio
-49.61
Dividend yield
0.00%
52-week range
$42.08 – $86.74
Volume
1.52M
Avg. volume
2.43M

Price performance · IONS

IONS price history

1M range · 20 trading sessions · Daily adjusted prices

Prices through Oct 30, 2026

IONS closed at $43.52 after 20 trading sessions, up 0.05% for the selected period.

Last close
$43.52
Period change
+0.05%
Period low
$42.38
Period high
$45.40
Daily close
View OHLC price history
IONS OHLC price history, latest 40 sessions
DateOpenHighLowCloseVolume
Oct 30, 2026$44.69$45.115$43.27$43.521.52M
Oct 29, 2026$45.57$45.84$44.04$44.391.83M
Oct 28, 2026$43.16$44.95$43.05$44.901.72M
Oct 27, 2026$43.23$44.10$43.02$43.962.38M
Oct 26, 2026$43.00$43.92$42.76$43.423.2M
Oct 23, 2026$43.80$43.80$42.58$42.933.02M
Oct 22, 2026$45.02$45.15$43.41$43.915.01M
Oct 21, 2026$45.55$45.76$44.26$44.272.27M
Oct 20, 2026$44.45$45.48$44.01$45.402.49M
Oct 19, 2026$43.33$44.54$43.00$44.383.1M
Oct 16, 2026$44.53$44.65$42.795$42.941.67M
Oct 15, 2026$43.58$44.71$43.4219$44.122.48M
Oct 14, 2026$42.22$43.47$42.08$42.702.03M
Oct 13, 2026$43.55$43.575$42.36$42.382.98M
Oct 12, 2026$45.37$45.455$43.62$43.671.95M
Oct 9, 2026$43.21$45.72$43.12$45.284.86M
Oct 8, 2026$43.76$44.19$42.79$43.303.35M
Oct 7, 2026$43.75$44.26$43.53$44.162.94M
Oct 6, 2026$44.185$44.665$43.17$44.002.19M
Oct 5, 2026$43.75$43.96$42.63$43.502.87M

Latest IONS news

The latest Smart Investors Daily articles mentioning IONS.

IONS research

Overview

Company profile and research snapshot.

Company profile

Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis received FDA approval in 2024 for Tryngolza for a rare high-triglyceride syndrome, marking its first independent launch.

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Analyst outlook

Consensus and target data currently published for this company.

Consensus
—
Average target
$83.85
Implied upside
—
Analysts
—
IONS recent ratings
DateFirmRatingTarget
Oct 22, 2026BMO CapitalOutperform—
Oct 15, 2026UBSBuy—
Sep 24, 2026HC Wainwright & Co.Buy—
Sep 22, 2026JP MorganOverweight—
Sep 15, 2026GuggenheimBuy—
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News briefing

No generated briefing is available yet.

AI research layers

Interpretive context generated from the platform’s current data sources.

No results

AI research layers have not been published yet.