Pfizer (PFE) Price Target Boosted to $27—Find Out Why!

Dividend Policy, History & Yield

Pfizer is a longstanding dividend-paying blue chip. The company currently distributes $0.41 per share quarterly (or about $1.64 annualized) and has stated it has “no plans to cut its quarterly dividend” despite recent earnings pressures (apnews.com). At the latest stock price (~$25–26), that payout equates to a robust dividend yield around 6.5–7%, one of the highest in Big Pharma (moneyweek.com). This yield has swelled in part because Pfizer’s share price declined over the past year, reflecting investor concerns about earnings declines and drug sales (more on that below).

Dividend History: Pfizer has a decades-long track record of paying quarterly dividends. It typically increased its dividend annually in the past, though growth has been modest (for example, the quarterly rate rose from $0.39 to $0.41 in 2022-2023). The current trailing twelve-month (TTM) dividend payout is $1.72 per share, as of January 2026 (www.macrotrends.net). Pfizer continued dividends even through major corporate changes like the 2020 spin-off of its off-patent drugs unit (Viatris) (www.macrotrends.net), underscoring management’s commitment to return cash to shareholders.

Dividend Coverage: A key question is whether Pfizer’s earnings and cash flows comfortably cover its dividend. In the pandemic boom, coverage was ample – Pfizer generated massive free cash flow of ~$26 billion in 2022 (www.macrotrends.net) thanks to COVID-19 vaccine/treatment sales, far exceeding the roughly ~$8–9 billion annual dividend outlay. However, as COVID product demand faded, cash flows dropped sharply. In 2023 Pfizer’s free cash flow plunged to only about $4.8 billion (www.macrotrends.net) (an 82% decline from 2022), which fell well below the dividend requirement. This raised concerns about sustainability, though Pfizer tapped its cash reserves and remained adamant about maintaining the payout (apnews.com). By 2024, free cash flow rebounded to $9.8 billion (www.macrotrends.net) as sales stabilized and costs were cut, roughly covering that year’s dividends. The dividend payout ratio in 2024 hovered around 60–70% of adjusted earnings (guidance ~$2.85 EPS vs. $1.64 dividend) – a high but manageable level (apnews.com) (apnews.com). Investors are watching whether Pfizer’s future earnings growth will strengthen dividend coverage or if a prolonged earnings slump could pressure the payout. For now, the company’s sizable cash balance and management’s stance suggest the dividend is safe, but the elevated yield reflects market caution.

Leverage and Debt Maturities

Pfizer’s balance sheet leverage has increased following a series of acquisitions. In 2023, the company took on significant debt to finance its $43 billion acquisition of cancer biotech Seagen, nearly doubling long-term debt that year. Pfizer’s total debt stood around $61 billion by mid-2025 (tradingeconomics.com), up from roughly $33 billion at the end of 2022 (www.macrotrends.net). This jump was largely due to a $31 billion multi-tranche bond offering in May 2023 (www.pfizer.com), which funded the Seagen deal. The new bonds were issued across maturities ranging from 2025 to 2063, with interest rates mostly in the mid-4% to low-5% range (www.pfizer.com) (www.pfizer.com). For example, Pfizer added $3 billion of notes due 2025 and another $3 billion due 2026, as well as longer-term notes maturing in 2030, 2033, and beyond (www.pfizer.com).

Maturity Profile: Despite the large debt increase, Pfizer laddered its maturities over multiple decades, reducing refinancing risk. Near-term debt obligations are modest – e.g. ~$3 billion due in 2025 and again in 2026 from the recent issuance (www.pfizer.com) – which should be manageable given Pfizer’s cash generation and access to capital. The bulk of Pfizer’s debt now matures in the 2030s and much later, giving the company time for new drugs and acquisitions to contribute before big repayments come due. Pfizer also ended 2024 with long-term debt slightly reduced to ~$57.4 billion (www.macrotrends.net) (www.macrotrends.net), indicating it has begun paying down or refinancing portions of the load.

Leverage Ratios and Coverage: Pfizer’s net debt-to-EBITDA remains reasonable for a large pharma, though higher than pre-acquisition levels. The company retains a strong investment-grade credit rating (in the A/Aa categories by major agencies) backed by its substantial revenues and cash flows. Interest expense has risen with the new debt (the 2023 bonds carry ~5% coupons (www.pfizer.com)), but coverage is still healthy – operating profits cover interest many times over. In 2024, for instance, Pfizer earned over $4.4 billion in Q3 profit alone (apnews.com); annual interest costs (likely in the $2–3 billion range) are well covered by expected 2024 EBIT on the order of ~$15+ billion. Overall, Pfizer’s leverage is elevated compared to its recent past, but remains in line with big-pharma peers. The company is using debt capacity to acquire new growth assets, and its stable cash flows from a diversified drug portfolio support the higher debt load.

Valuation and Comparables

One reason some analysts see upside to a $27 stock price is Pfizer’s undemanding valuation. The market has significantly de-rated Pfizer due to its earnings decline, leaving the stock trading at a single-digit price-to-earnings ratio and a discount to peers. At around $25 per share, Pfizer’s forward P/E is only ~8–9x expected earnings (moneyweek.com). In early 2026, Pfizer had a forward P/E of 8.4 and a dividend yield near 6.9% at a ~$24.90 stock price (moneyweek.com). This is considerably cheaper than many pharmaceutical peers: for example, AstraZeneca trades around 18x forward earnings with a 1.8% yield, Merck & Co. at ~11x with a 3.2% yield, and GlaxoSmithKline (GSK) about 9.5x with a 3.5% yield (moneyweek.com) (moneyweek.com). Even Sanofi and Johnson & Johnson yield just ~4–5% at ~10–13x earnings. By comparison, Pfizer’s 6–7% yield and low multiple stand out as a value opportunity (moneyweek.com) – if its earnings and dividend can be sustained.

From another angle, Pfizer’s stock is cheaper than it’s been in years on an absolute basis. The shares have fallen roughly 32% over the past five years (2019–2024) (moneyweek.com), erasing the pandemic-era gains. That drop was mainly driven by the comedown in COVID-19 vaccine profits (moneyweek.com) and worries over upcoming patent expirations. Now, with the stock in the mid-$20s, much of that bad news may be priced in. Pfizer’s enterprise value (market cap plus net debt) is only about 2.5 times its 2024 sales (~$63.6B revenue) (moneyweek.com) – a relatively low EV/Sales ratio for a pharma leader with several blockbuster drugs and vaccine franchises. On a cash flow basis, Pfizer’s free cash flow yield (FCF/price) improved to around 6–7% in 2024 (with ~$9.8B FCF on a $147B market cap) and could rise if earnings normalize.

Wall Street’s consensus price targets have been subdued, but the tide may be turning. The $27 target implies roughly a market-average P/E in the low double-digits on a post-2024 earnings rebound. It’s not aggressive – indeed Bank of America recently lowered its Pfizer target to $28, citing near-term challenges (www.kiplinger.com) – but it reflects a view that Pfizer is undervalued relative to its long-term fundamentals. The stock’s hefty dividend yield provides potential downside support for value investors. If Pfizer can navigate the next few years of patent losses and bring new drugs to market, there is room for multiple expansion. In sum, valuation is a clear positive in the bull case: Pfizer offers a bargain-bin earnings multiple and a cash payout that pays investors to wait for a turnaround.

Key Risks, Red Flags, and Open Questions

Despite the attractive yield and valuation, Pfizer’s path to upside is not without significant risks. Understanding these headwinds is crucial to evaluating the $27 price target:

- Patent Expirations (“Loss of Exclusivity”): Pfizer is in the midst of a multi-year wave of patent cliffs that will pressure revenue. Notably, several blockbuster drugs face loss of exclusivity (LOE) through 2026–2029, meaning generic competition will erode their sales. Bank of America’s analysts struggle to see a near-term “re-rating catalyst” for Pfizer’s stock “as Pfizer works through its multi-year loss of exclusivity period… expected to end in 2029.” (www.kiplinger.com). This looming LOE period for drugs like blood thinner Eliquis (co-marketed with BMS), cancer drug Ibrance, and others is a primary reason for tempered earnings outlooks. The key question: can Pfizer’s pipeline and acquisitions fill the gap left by these expirations? Until new revenue streams ramp up, sales and earnings may stagnate, which could keep the stock range-bound.

- Post-Pandemic Earnings Decline: Pfizer’s COVID-19 vaccine (Comirnaty) and antiviral (Paxlovid) generated an unprecedented windfall in 2021–2022. As the pandemic receded, those sales collapsed – Comirnaty and Paxlovid combined fell from over $56 billion in 2022 to just a few billion expected in 2024 (apnews.com) (apnews.com). Management projected only ~$8 billion in COVID product revenue for 2024 (apnews.com), versus Wall Street’s prior hopes of $13B, forcing Pfizer to slash its earnings forecasts. Indeed, Pfizer guided 2024 earnings per share of $2.05–$2.25, dramatically below analyst consensus of ~$3.17 (apnews.com). This reset led to a major selloff (the stock fell 8% in one day, to ~$26 (apnews.com)). While 2024 outlook later improved (thanks to a late-year COVID uptick) with Pfizer raising EPS guidance to ~$2.85 (apnews.com), the volatility in pandemic-related demand underscores ongoing uncertainty. Open question: what is Pfizer’s “normal” earnings power post-COVID? If core revenues (excluding the one-time vaccine boom) don’t grow, the current low valuation may actually be fair. Bulls are betting that 2023 was the trough, but this will depend on successful new product launches.

- Pipeline and R&D Productivity: Pfizer’s future hinges on replacing lost sales with new drugs and vaccines. The company has many programs in development – e.g. three Phase 3 vaccines (for COVID, Lyme disease, and Streptococcus) and several oncology drugs in trials (moneyweek.com) – and it has been acquisitive to bolster its pipeline. However, there are concerns about Pfizer’s internal R&D productivity. Pfizer invests about 17% of revenue into R&D, which is significantly less than some peers like Merck (~28%) or Eli Lilly (~24%) (moneyweek.com). This leaner R&D budget has coincided with many Pfizer pipeline projects being incremental “product enhancements” (e.g. new uses or formulations of existing drugs) rather than breakthrough new compounds (moneyweek.com). It raises the question: Can Pfizer innovate sufficiently? Or will it continue relying on M&A for growth? The company’s recent acquisitions – including Array (oncology), Arena (immunology), Global Blood Therapeutics (sickle cell), Biohaven (migraine), and Seagen (cancer) – bring promising assets, but integration and actual results will tell if those investments pay off. In fact, activist investor Starboard Value has taken aim at Pfizer’s strategy, questioning the “returns from a string of recent acquisitions” made with the COVID windfall (apnews.com). Starboard’s CEO suggested Pfizer needs to create more value for shareholders and is pressing the board on this (apnews.com). How management balances internal innovation vs. further acquisitions (or even divestitures) remains an open question.

- Dividend Sustainability: Pfizer’s dividend is generous – perhaps too generous relative to current earnings. With the payout ratio rising above 70% of forward earnings in 2023–24, the dividend’s sustainability will depend on earnings recovering. So far, Pfizer has been adamant about preserving the dividend (even expanding a cost-cutting program rather than cut the payout) (apnews.com) (apnews.com). But if business results disappoint for an extended period, a high yield could signal a potential cut down the road (as has happened with other high-yielding stocks in distress). Investors should watch 2025–2026 earnings trends: if Pfizer cannot grow EPS back well above $3, maintaining the $1.64+ dividend may become challenging. Management’s confidence (and sizable cash on hand) suggests a cut is unlikely in the near term. Nonetheless, the elevated yield reflects the market’s cautious view. Any hint of a dividend reduction would likely hurt the stock – conversely, if Pfizer navigates this trough without a cut, income-focused investors may gain more trust in the company.

- Regulatory and Pricing Pressures: Like all pharma companies, Pfizer faces political and regulatory risks around drug pricing. The U.S. Inflation Reduction Act now enables Medicare to negotiate prices on top-selling drugs; Pfizer’s anticoagulant Eliquis is among the first drugs slated for negotiation. While the exact impact is uncertain, such measures could trim future revenue on mature products. Additionally, healthcare policy shifts or intellectual property law changes could affect how Pfizer prices its medications globally. These factors add another layer of long-term risk outside of the company’s direct control.

- Macro and Other Risks: Broader macroeconomic factors (interest rates, currency exchange rates, etc.) can also influence Pfizer. Higher interest rates increase borrowing costs and can hurt high-dividend stocks’ appeal. Pfizer’s international operations mean a strong dollar can dent foreign sales. Finally, unforeseen issues like major litigation or safety concerns with a key product could pose “red flag” events. One notable recent safety issue was with JAK inhibitor drugs (including Pfizer’s Xeljanz) which saw usage limitations due to side effects. So far, nothing alarming is on the radar, but pharma investors must always be mindful of clinical and legal risks that can emerge suddenly.

The Bottom Line

The decision to boost Pfizer’s price target to $27 reflects a view that the stock’s risk/reward profile is improving. Pfizer today offers a rich dividend and trades at a bargain valuation, which could reward patient investors if the company executes well. The company’s strong balance sheet and cash flows have allowed it to invest in future growth while maintaining shareholder payouts. Indeed, even as near-term earnings are under pressure, Pfizer’s management emphasizes its commitment to the dividend and to rejuvenating its pipeline (organically and via acquisitions) (apnews.com) (apnews.com).

However, this optimism must be balanced against the real challenges Pfizer faces: a “hole” in revenues as COVID sales wane and big drugs lose exclusivity, and the need to prove that recent deals like Seagen will produce the next generation of blockbusters. It may take several years for Pfizer’s R&D and dealmaking to bear fruit. Bank of America’s analyst captured this duality by remaining neutral on PFE stock despite its low price—acknowledging the “attractive valuation and solid ~6.5% dividend yield” yet seeing little catalyst for a higher re-rating until late this decade (www.kiplinger.com). In other words, Pfizer might be a waiting game.

Why $27? For investors with a long-term horizon, $27 is arguably a conservative price target that Pfizer could reach as it works through its current challenges. This level factors in a cautious outlook but still assumes Pfizer’s earnings stabilize and its valuation reverts upward modestly. Achieving $27 (or higher) will likely require confidence that Pfizer’s pipeline can start offsetting LOEs and that its hefty dividend remains intact. Positive surprises – such as stronger-than-expected new drug launches, successful cost cuts, or strategic moves prompted by activist pressure – could accelerate a recovery in the share price. On the flip side, any stumble (e.g. a dividend cut or pipeline failure) could undermine the bull case.

Investor Takeaway: Pfizer’s stock appears cheap for a reason, but also offers considerable value if the company can navigate the next few years. The boost to a $27 target suggests that at least some analysts see the downside as limited from here, given the stock’s low valuation and income return. Investors should monitor upcoming earnings, pipeline news (especially in oncology and vaccines), and management’s capital allocation moves. Pfizer is a fundamentally strong enterprise with global franchises – the question is when that strength translates back into growth and a higher stock price. In the meantime, shareholders are being paid handsomely to wait, with a dividend yield that is among the highest in the S&P 500 (moneyweek.com). Whether Pfizer is a classic value play or a value trap will become clearer in the next 1–2 years. For now, $27 is a reachable target that factors in both the company’s notable challenges and its enduring strengths, making Pfizer a stock to watch for a potential turnaround.

Sources: Financial filings and investor presentations; Pfizer press releases and SEC reports; Associated Press reports on Pfizer’s earnings and guidance (apnews.com) (apnews.com) (apnews.com); MoneyWeek and Kiplinger analysis providing peer comparisons and analyst commentary (moneyweek.com) (www.kiplinger.com); MacroTrends financial data on debt and cash flows (www.macrotrends.net) (www.macrotrends.net); and Pfizer Investor Relations statements. All information is up to date as of the latest available reports.